smoking active versus placebo cannabis impacts tobacco cigarette smoking behavior H e a l t h M e d i c a l

please respond to the following discussion post as a peer commenting on the post. The purpose of the study that I chose was to determine the effects of smoked cannabis and tobacco which involved male human subjects. The objective of this placebo-controlled, double-blind, within-subjects human laboratory study was to gather preliminary data on how smoking active versus placebo cannabis impacts tobacco cigarette smoking behavior, craving, and subjective effects. During the study, participants smoked one cannabis cigarette, and approximately 30 minutes later were given a 5-min ad libitum period to smoke one of their own brands of tobacco cigarettes (Peters et al., 2021).

Ethical considerations that were observed in this study were that the voluntary participants had to first endure a screening to qualify. The participants had to be healthy, ages 18-55, and had to be active cannabis and tobacco users. The chosen participants had to then provide informed consent to participate in the study. These individuals were then closely monitored so they would not experience excessive intoxication or other negative effects from cannabis. These measures were done to ensure participant safety during the study.

The study products were approved by the National Institute on Drug Abuse and the U.S. Drug Enforcement Administration. Lastly, the procedures of the study were approved by the Battelle Institutional Review Board, U.S. Drug Enforcement Administration, U.S. Food and Drug Administration, and National Institute on Drug Abuse Drug Supply Program. The study was also registered on clinicaltrials.gov.

Ethical considerations in research are similar to ethical considerations when providing health care services because they both must provide consent that the patient or participant is willing to participate in a study or to receive health care services. Also, both must ensure that patients’ and participants’ safety and well-being are a top priority.

Reference:

Peters, E. N., Herrmann, E. S., Smith, C., Wilhelm, J. A., Koszowski, B., Halquist, M., Kosmider, L., Poklis, J., Roth, S., Bart, S., & Pickworth, W. B. (2021). Impact of smoked cannabis on tobacco cigarette smoking intensity and subjective effects: A placebo-controlled, double-blind, within-subjects human laboratory study. Experimental and Clinical Psychopharmacology, 29(4), 345–354. https://doi.org/10.1037/pha0000391